NGS is also known as high-throughput sequencing and can be used to indicate a range of gene sequencing technologies that can improve the original Sanger sequencing process. In addition to reducing the cost and time of DNA and RNA sequencing, next-generation sequencing can also sequence smaller samples. Sample preparation is a new highlight in NGS. New reagents and instruments are constantly emerging to reduce time and increase throughput. At the same time, new methods are continually being developed to process fewer samples, such as single cells.
Global NGS Sample Preparation Market estimated to grow with a significant rate during the forecast period, 2020-2027. The increasing awareness about precision medicine and the high incidence of chronic diseases are expected to propel the global NGS sample preparation market in the upcoming years. Moreover, the upsurge in the adoption of genomics for developing innovative diagnostic tools and tests and the development of precision & personalized medicines will accelerate the growth of global NGS sample preparation market size in the estimated periods. Additionally, technological advancements in the field of NGS sample preparation have led to the availability of standardized sample preparation protocols that are driving the growth of the NGS sample preparation industry.
Furthermore, the rising prevalence of chronic disorders such as cancer, diabetes, inflammatory bowel disease, and autoimmune diseases has led to the demand for NGS sample preparation inn the expected periods. In addition, the evolution of integrated and automated informatics and mechanical protocols have brought about automation in NGS sample preparation such as it enhances sequencing speed & capacity, and sample tracking. The growing need for personalized treatment coupled with the surge in healthcare spending and improvement in healthcare technology is projected, driving the growth of the NGS sample preparation market.
The development of DNA and RNA sequencing technologies has accelerated the understanding of molecular characteristics of genetic diseases. The application of high-throughput sequencing, that is, next-generation sequencing (NGS) technology to detect the genetic characteristics of diseases. The rapid development of NGS technology has also accelerated the widespread application of this technology in clinical molecular diagnosis. According to different detection purposes, the clinical application of NGS technology is mainly divided into the following two strategies: designing appropriate chips for diseases of known etiology, and directly targeted genome sequencing of multiple known disease-causing genes and sequencing exomes or whole genomes for diseases of unknown etiology.
The most widespread application of targeted genome sequencing in clinical diagnosis is for the clinical diagnosis and treatment of cancer subtypes.
Based on product type, the global NGS Sample Preparation market categorized into Reagent & Consumables and NGS Workstations. The Reagent & Consumables segment witness to gain a major share in the market by 2027, attributable to these is deep well plates, pipettes, tips, high precision, and highly efficient during experiments.
The NGS Workstations segment will drive due to the increasing efficiency and reducing hands-on time and flexibility to maximize scheduling.
Based on workflow, the global NGS Sample Preparation market classified into Library Preparation [DNA, RNA], Target Enrichment (Targeted Sequencing, Whole Exome Sequencing, and Others), and Quality Control. The Library Preparation segment accounted for a higher revenue share in 2019, and it will grow substantially in the coming years. It is attributed to their help in generating a collection of DNA fragments for sequencing and used for ligation of barcoded molecular adaptors, end repair, and purification reactions.
The Target Enrichment will grow in the forecast periods due to its ability to process hundreds of millions of DNA templates in parallel. It includes Targeted Sequencing and Whole Exome Sequencing.
Based on technology, the global NGS Sample Preparation market classified into Sequencing by Synthesis (Sbs), Ion Semiconductor Sequencing, Single-Molecule Real-Time Sequencing (Smrt), Nanopore Sequencing, and Others. The Sequencing by Synthesis (Sbs) estimated to generate maximum revenue by 2027, on account of the sequencing by synthesis, helps in analyzing DNA quickly, accurately, and proves to be a cost-effective option and sequenced the entire human genome in few hours.
The Ion Semiconductor Sequencing will grow due to its help in DNA sequencing for the detection of hydrogen ions and enables to directly convert chemically encoded information into digital information on the semiconductor chip.
Based on application, the global NGS Sample Preparation market categorized into Diagnosis (Infectious Disease, Cancer Diagnostics, and Reproductive Health Diagnostics), Drug Discovery, Agricultural & Animal Research, and Others. Diagnosis segment expected to gain higher market share by 2027 owing to the increasing number of new cancer cases worldwide, and the surge in demand for new product development for cancer and NIPT.
Based on the end-user industry, the global NGS Sample Preparation market categorized into Academic Institutes & Research Centers, Hospitals & Clinics, Pharmaceutical & Biotechnology Companies, and Others. Academic Institutes & Research Centers segment expected to dominate the market by 2027 on account of the rising collaborations between NGS market players and academic & research institutions, and favorable funding scenario for genomics research.
Hospitals & Clinics segment will surge by the availability of upgraded third-generation sequencing technologies that facilitates diagnostic procedures.
Based on geography, the global NGS Sample Preparation market size segmented into North America, Europe, Asia Pacific, South America, and Middle East & Africa. North America estimated to occupy the lion’s market share by 2027, owing to the swelling NGS-based research & clinical applications in the region and favorable initiatives by government and private bodies for the development and adoption of NGS technologies.
The Asia Pacific will drive due to the rising preference for personalized medicine coupled with development in NGS bioinformatics and pre-sequencing solutions.
Companies such as Illumina Inc., Thermo Fisher Scientific, QIAGEN N.V., Agilent Technologies, Inc., Beckman Coulter, Becton, Dickinson and Company, Pacific Biosciences of California, PerkinElmer Inc., F. Hoffmann-La Roche, New England Biolabs, Inc., and NuGEN Technologies, Inc. are the key players in the global NGS Sample Preparation Market.