Nucleic acids are being isolated from various sources such as cells, PCR reactions, restriction enzyme digestions, and agarose gel matrices. There is a need for the highly pure and high quality of DNA and RNA for clinical applications and a wide variety of research. DNA and RNA need to be isolated from their respective hosts- eukaryotic cells, yeast, virus, plasmid, and bacteria for downstream applications such as cloning, PCR, sequencing, and blotting. Most clinical and research laboratories require some types of nucleic acid processing for diagnostics. Products such as phenol-chloroform can be used for extraction in association with equipment such as vacuum manifolds, or complete kits may be purchased to take the guesswork out of isolation. High throughput labs can take benefits of automated systems to streamline workflow and reduce repetitive stress. Choice of purification system will depend on the number of samples, volume, desired turnaround time, and state of the nucleic acid- fragment, chromosome, mRNA, supercoiled DNA, etc.
Global nucleic acid isolation and purification market size projected to grow at a CAGR of over 10.9% during 2020–2027. The market growth can be attributed to molecular diagnostics of infectious diseases, biodiversity assessment, marker-assisted selection, and genetic disorders. Further, the increasing implementation of nucleic acid in healthcare, forensics, food, and pharmaceutical industries is anticipated to fuel the demand for nucleic acid isolation and purification across the globe in the coming years. Additionally, the increasing applications in disease diagnostic such as cancer, congenital anomalies, and STDs are expected to witness remarkable growth of nucleic acid isolation and purification industry. Moreover, the rising R&D funding and technological advancement in genetics, and rising demand for personalized medicine, will foster market growth. Furthermore, the rise in demand for nucleic acid-based products and therapeutics such as DNA vaccines and RNA-based drugs positively impacts the demand for nucleic acid isolation and purification in the future. The surge in preferences for robust, efficient, fast, and easy solutions with the availability of a wide range of reagent kits and purification systems will promulgate the global nucleic acid isolation and purification market share.
The nucleic acid isolation and purification systems and kits offer maximum yield and purity, and also the cost associated with the genetic sequences is reduced. Factors like developing new drugs, personalized medicine, and diagnosis of diseases including cancer, genetic disorders & gene mutations, and other infectious diseases will boost the market’s growth. Moreover, Nucleic Acid Isolation and Purification play a crucial role in pharmaceutical companies. It involves the initial step for developing a new therapeutic that has promising demand in the market. However, the Instrument’s cost is high, which can be restraint of the market.
The global nucleic acid isolation and purification market are classified into instruments, kits, and reagents based on product. The kits segment accounted for the highest market share in 2019. It is attributable to its easy use, low cost, and wide range of applications such as molecular diagnostics, gene cloning, and sequencing.
The instruments segment will garner a significant market share in the forecast period. It is owing to fast, reliable, and robust technology. It also offers vast research applications, including bio-banking, HLA typing, virus & bacteria detection, and human genetics.
Based on the technology, the global nucleic acid isolation and purification market is segregated into column-based, reagent-based, and magnetic bead-based isolation and purification. The column-based segment held a higher revenue share in 2019 and is projected to dominate the nucleic acid isolation and purification market by 2027. It is primarily attributed to its increasing use in diagnostic laboratories. Moreover, it doesn’t require the number of hazardous chemicals used in traditional nucleic acid extraction procedures, and it is a faster, cost-effective, and simpler method than others.
The Magnetic bead-based segment will grow with a lucrative growth rate in the forecast period due to the high efficiency in the variety of samples at any throughput and high demand in downstream applications.
Based on application, the global nucleic acid isolation and purification market are classified into PCR clean-up, genomic DNA, Micro RNA, Blood RNA, mRNA, Plasmid DNA, and Total RNA isolation and purification. The DNA isolation and purification segment will garner higher market potential by 2027. It is due to the easy, rapid, and inexpensive method.
Based on End-user, the global nucleic acid isolation and purification market is classified into pharmaceutical & biotechnology companies, academic & research institutes, CROs, and Hospital &diagnostic centers.
Hospitals & diagnostic centers are slated to account for a significant share by 2027. The growth of the segment can be attributed to the increasing demand for molecular diagnostic tests and therapeutics.
By geography, the global nucleic acid isolation and purification market are segmented into North America, Europe, Asia Pacific, South America, and Middle East & Africa. North America is slated to account for a significant share by 2027 in the nucleic acid isolation and purification market. The growth in the region can be allocated to the increasing R&D sector and high investment made by the pharmaceutical industries.
Europe is expected to the significant growth opportunities due to rising awareness regarding the nucleic acid method in different sectors.
Companies such as Agilent Technologies, Biolabs, Bio-Rad Laboratories Inc, Danaher Corporation, F. Hoffmann-La Roche Ltd, GE Healthcare, Roche AG, Merck KGaA, Promega Corporation, Illumina Inc, Takara Bio Inc, Qiagen NV, and Thermo Fisher Scientific Inc are the key players in the global nucleic acid isolation and purification market.