HSC is used to identify substances such as small molecules, peptides, or RNAi that alter the phenotype of a cell in the described manner. It is widely used in biological research and drug discovery. High-content screening is a powerful approach for the multi-parametric analysis of cellular events. It allows the quantitative analysis of complex cellular/organoid events and visualization of the relevant phenotypes. HSC is highly adapted in pharmaceutical industries to improve in-vitro toxicity testing by reducing the time and cost.
The global high-content screening market size was valued at USD 1318.8 million in 2020 and projected to reach USD 4045.8 million by 2027, growing at a CAGR of 13.57% during the forecast period, 2020-2027. The major factors are the rising need for cost containment in pharmaceutical R&D and the increasing demand for reduction in time during drug discovery. Additionally, the increasing demand for determination and study of toxicity levels in the initial phases of drug discovery will spur the global high-content screening industry in future periods. Furthermore, the growing public-private funding for cellular research and the advanced development of HSC products is expected to witness remarkable growth of high-content screening. The increasing demand for the determination & study of toxicity levels at an early stage of drug discovery is expected to reach the demand for high-content screening over the coming years.
Furthermore, the rapidly expanding customer base, the rise in the extensive R&D activities at the academic and industrial level, and the increasing scope of biomedical applications fuel the demand for the high-content screening market. The growing advancement in imaging instruments & informatics solutions and rising government funding for the development of novel drugs will bolster the growth of global high-content screening market share. Additionally, the growing geriatric population or increasing healthcare demands in the developing world generating the growth of the high-content screening market across the globe.
High-throughput screening is a drug discovery process that allows automated testing of huge numbers of chemical & biological compounds for a specific biological target. It is a highly useful tool in the pharmaceutical industry, leveraging robotics and automation to quickly test the biological or biochemical activity of many molecules, usually drugs. HSC accelerates target analysis, as it can quickly screen large-scale compound liabilities in a cost-effective way. However, restrictions are often challenging to achieve. Also, the cost of screening instruments is high, and a lack of skilled professionals is expected to hinder the market’s growth.
The global high-content screening market is segregated into instruments, consumables, software, services, and accessories based on the product and service.
The instrument segment is estimated to witness growth over the analysis timeframe due to the rise in adoption of screening instruments, technological advances in instrumentation, and rapid expansion in the customer base.
The software will grow significantly due to the rising screening system adoption, technological advancements in image acquisition and storage capabilities.
Based on the application, the global high-content screening market is classified into target identification & validation, primary screening & secondary screening, toxicity studies, compound profiling, and other applications.
The surgical guides are expected to be the highest revenue share for high-content screening during the forecast period. The segment’s growth is mainly attributed to the presence of many potential drug candidates for target-specific delivery and the rising use of HCS for secondary screening purposes.
The toxicity studies will witness a lucrative growth rate in the estimated period due to highly used to measure the in-vitro toxicity of environmental compounds.
Based on the end-user, the global high-content screening market is segmented into pharmaceutical and biotechnology companies, academic & government institutes, and contract research organizations.
The pharmaceuticals and biotechnology companies segment will dominate the global high-content screening market by 2027. Due to the increasing use of HSC in clinical trial settings, early stages of drug development and drug discovery.
The CRO accounted for the largest share of the high-content screening market in 2019 because of the increasing number of CROs offering HCS services and the rising demand for outsourced service providers in HCS.
By geography, the global high-content screening market segmented into North America, Europe, Asia Pacific, South America, and Middle East & Africa. North America is estimated to project considerable growth over 2020-2026. It is due to advents in technology, leading industry players offering innovative products, and increasing healthcare expenditure.
The Asia Pacific will capture a defined share of the high-content screening market by 2027. Due to the increasing research in drug discovery, we are continually improving healthcare infrastructure in the region and mounting health care expenditures in developing countries such as India and China.
Companies such as Danaher Corporation, Thermo Fisher Scientific Inc, Becton Dickinson and Company, GE Healthcare, Bio-Rad Laboratories, BioTek Instruments Inc, Tecan Group, PerkinElmer Inc, Merck Millipore, Molecular Devices LLC, and Yokogawa Electric Corporation are the key players in the global high-content screening market.
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